Cuyuni-Mazaruni (Region 7) is a region of Guyana. Venezuela claims the territory as part of Guayana Esequiba. It borders the regions of Barima-Waini, Essequibo Islands-West Demerara and Pomeroon-Supenaam to the north, the region of Upper Demerara-Berbice to the east, the region of Potaro-Siparuni and Brazil to the south. Its capital is Bartica, with other towns including Issano, Kartuni, Kamarang, Keweigek, and Imbaimadai. It covers an area of 47,213 km². Before the 1980 administrative reform most of the area belonged to the Mazaruni-Potaro district.
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