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Ayase (綾瀬市, Ayase-shi) is a city located in Kanagawa Prefecture, Japan. It is on the east bank of the Sagami River, and is bordered by Yamato, Fujisawa and Ebina cities. It should not be confused with a neighborhood of the same name in the special ward of Adachi, Tokyo.
As of April 2017, the city has an estimated population of 84,309, with 33,899 households, and a population density of 3,800 persons per km2. The total area is 22.28 km2 (8.60 sq mi).